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Abstract: Bioluminescent and fluorescent reporter systems have enabled the rapid and continued growth of the optical imaging field over the last two decades. Of particular interest has been noninvasive signal detection from mammalian tissues under
Abstract: Background The bacterial luciferase (lux) gene cassette consists of five genes (luxCDABE) whose protein products synergistically generate bioluminescent light signals exclusive of supplementary substrate additions or exogenous manipulations. Historically expressible only in prokaryotes, the
The study used a humanized, bacteria-originated lux reporter system consisting of six (luxCDABEfrp) genes to express components required for producing bioluminescent signals in human UBC J82, J82-Ras, and SW780 cells without exogenous substrates.
Cell viability assays are extensively used to determine cell health, evaluate growth conditions, and assess compound cytotoxicity. Most existing assays are endpoint assays, in which data are collected at one time point after termination of the experiment.
Intersex as the manifestation of testicular oocytes (TO) in male gonochoristic fishes has been used as an indicator of estrogenic exposure. Here we evaluated largemouth bass (Micropterus salmoides) or smallmouth bass (Micropterus dolomieu) form 19 National Wildlife Refuges (NWRs) in the Northeast U.S. inhabiting waters on or near NWR lands for evidence of estrogenic endocrine disruption.
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490 BioTech is pleased to announce the acquisition of a Phase II SBIR award from the National Institutes of Health, National Institute of General Medical Sciences for the development of new high-throughput drug discovery screens
490 BioTech is pleased to announce a Phase II STTR award from the National Institutes of Health, National Institute of General Medical Sciences, that will enable the development of novel in vitro cellular and in
490 BioTech is proud to announce that Funakoshi Co., Ltd. has joined our distributor network to serve our research clientele in Japan.
SouthFound Media recently interviewed Dan Close, 490 BioTech’s Chief Science Officer, to discuss our autobioluminescent technology and the newest research we are pursuing. SouthFound specializes in helping Southern startups and entrepreneurs get focused, get funding,
490 BioTech will be speaking at the SOT 56th Annual Meeting and ToxExpo in Baltimore, Maryland from March 12-16, 2017. This year’s meeting, like its predecessors, is designed to provide you with access to cutting-edge
490 BioTech’s Conflict of Interest policy is available for public review at this LINK.
490 BioTech is pleased to announce distributor partnerships with Applied StemCell (USA, Japan), Proteigene (European Union, United Kingdom), and BioAspect Services About Applied StemCell: “Applied StemCell Inc. (ASC) is a fast growing biotechnology company headquartered
490 BioTech went to space on-board the SpaceX Falcon 9 rocket for the 14th resupply mission to the International Space Station on 4:30 p.m. EDT, Monday, April 2nd. Read all about our autobioluminescent cell lines
