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Cardiomyocytes transected with 490 BioTech’s Ready-To-Use Autobioluminescent Toxicity Assay Mix continuously reporting changes in metabolic activity over a 40-hour period. The easily identified autobioluminescent signal reveals when effects occur, how long they last, and if they are permanent. Non-destructive autobioluminescence allows the 5 samples in this example to replace 12,000 samples using older luciferin-requiring bioluminescent technologies.
490 BioTech is proud to provide contract metabolic activity/toxicity services using our proprietary autobioluminescent technology.
Our autobioluminescent human tissue models continuously and non-invasively track metabolic dynamics over prolonged exposure periods to identify both pre- and post-metabolism compound effects. Contact us today to learn how we can put autobioluminescent monitoring to work for you.
Do you have a specialty or proprietary tissue that can benefit from autobioluminescent expression?
We can modify your existing cell lines to produce data continuously without costly and potentially influential substrate addition or sample destruction. We can quickly modify your samples to express an autobioluminescent phenotype and return them to your laboratory for in-house testing at a fraction of the cost of purchasing and maintaining an existing, substrate-requiring cell line.
Our revolutionary new approach to optical imaging provides you with increased data acquisition in both tissues and small animal models. By taking advantage of our continuously light producing human cell lines it has finally become possible to break free from the expensive and error prone introduction of substrate.
Get back to doing what you do best – getting data.