Cardiomyocytes transfected with 490 BioTech’s Ready-To-Use Autobioluminescent Toxicity Assay Mix continuously reporting changes in metabolic activity over a 40-hour period. The easily identified autobioluminescent signal reveals when effects occur, how long they last, and if they are permanent. Non-destructive autobioluminescence allows the 5 samples in this example to replace 12,000 samples using older luciferin-requiring bioluminescent technologies.
Do you have a specialty or proprietary tissue that can benefit from autobioluminescent expression? Do you need a kit for tracking transcriptional activation in real-time?
We can modify your cell line to produce data continuously without costly and potentially influential substrate addition or sample destruction, or create a custom kit for tracking target gene expression without perturbing your samples.
Let our passion for developing autonomously bioluminescent solutions become the pathway to your next success.
490 BioTech can help you find your next compound by providing contract metabolic activity and toxicity screening services using our proprietary autobioluminescent technology.
Our autobioluminescent cellular models continuously track metabolic dynamics over prolonged exposure periods to identify both pre- and post-metabolism compound effects so you can learn more about your compound’s effects.
Contact us today to learn how autobioluminescent monitoring can work for you and de-risk your discovery pipeline.